24,000 BCE
Krona violates Oan law, using Oan super-science to travel to the beginning of time where he inadvertantly corrupts all of creation with entropy.
The Maltans collectively choose to police the universe against their own creation. The Maltan scientists and philosophers, collectively called the Guardians, disagree with the Maltan leadership and warriors, collectively called the Controllers, in the proper way to do this but are overruled, and the Manhunters are born.